All Research Reviews

Every article published on Cancer Prevention Lab, sorted by date.

Treatment · 9 min read

Mebendazole for Lung Cancer

Phase I/II data in small cell lung cancer. Microtubule disruption mechanism, crosses blood-brain barrier.

🔬 Grade B: Promising
Treatment · 9 min read

Itraconazole for Lung Cancer

Phase II trial in NSCLC showing 72-79% tumor growth reduction in xenograft models. Hedgehog + VEGFR2 pathway inhibition.

🔬 Grade B: Promising
Treatment · 10 min read

Disulfiram (Antabuse) + Copper for Cancer

Phase II trials in GBM, breast, and pancreatic cancer. Cuproptosis mechanism discovered in 2022. Cancer stem cell elimination.

🔬 Grade B: Promising
Treatment · 12 min read

The Press-Pulse Protocol

Thomas Seyfried's metabolic framework targets both glucose and glutamine simultaneously. The most complete dietary-metabolic approach to cancer management.

🔬 Grade B: Promising
Early Detection · 8 min read

The Galleri Test: Is $950/yr Worth It?

A blood test that detects 50 cancer types. PATHFINDER 2 trial showed 7x cancer detection. We analyze what that actually means.

Grade A: Strong Evidence
Prevention · 9 min read

High-Dose Melatonin: The 34% Mortality Reduction

Meta-analysis of 8 RCTs shows melatonin at 10-20mg reduced cancer mortality by 34%. No toxicity ever established.

🔬 Grade B: Promising
Treatment · 12 min read

High-Dose IV Vitamin C: The Trial That Doubled Survival

A Phase II RCT doubled overall survival in metastatic pancreatic cancer. We break down the Iowa trial, mechanism, and what it means.

Grade A: Strong Evidence
Treatment · 10 min read

Mebendazole: The $5 Cancer Drug

An FDA-approved dewormer with Phase I/II trial data in glioblastoma and colorectal cancer. Crosses the blood-brain barrier.

🔬 Grade B: Promising
Debunked · 8 min read

Alkaline Diet Cancer Myth

The alkaline diet hypothesis has been debunked. Blood pH is tightly regulated regardless of diet. Tumor pH is already acidic. No clinical trial supports this.

Grade DEBUNKED: Debunked
Comparison · 12 min read

Curcumin vs Berberine for Cancer

Both have preclinical anticancer data. Curcumin has more research but terrible bioavailability. Berberine absorbs better but has less cancer-specific data.

🔶 Grade C: Early / Limited
Comparison · 11 min read

Ivermectin vs Mebendazole for Cancer

Mebendazole has Phase I/II glioblastoma trial data showing survival benefit. Ivermectin only has preclinical data. Mebendazole wins on evidence.

🔬 Grade B: Promising
Treatment · 9 min read

Quercetin for Cancer

Senolytic flavonoid that clears chemotherapy-induced senescent cells. D+Q combination in early human trials. Low oral bioavailability remains a problem.

🔶 Grade C: Early / Limited
Treatment · 9 min read

Mistletoe (Iscador) for Cancer

Used in German integrative oncology for decades. Quality of life benefits documented in RCTs. Survival benefit unproven but cohort studies are intriguing.

🔶 Grade C: Early / Limited
Treatment · 10 min read

CBD Oil for Cancer

Cannabidiol shows apoptosis, angiogenesis inhibition, and metastasis suppression in lab models. Human evidence is anecdotal. Grade C.

🔶 Grade C: Early / Limited
Treatment · 10 min read

Turkey Tail Mushroom and Cancer

PSK (polysaccharide-K) approved as cancer adjuvant in Japan since 1977. Cochrane review found significant survival benefit in GI cancers with chemotherapy.

🔬 Grade B: Promising
Treatment · 11 min read

Artemisinin for Cancer

Iron-dependent oxidative stress selectively toxic to cancer cells. Phase I/II trials show safety and early signal. One of the most compelling off-patent compounds.

🔬 Grade B: Promising
Debunked · 7 min read

Metformin for Cancer: The Trial That Killed the Hypothesis

The MA.32 RCT (3,649 patients, JAMA 2022): HR 1.01. Absolutely no benefit. The observational data was biased.

⚠️ Grade D: Weak / Mixed